Decreased Sp1 Expression Mediates Downregulation of SHIP2 in Gastric Cancer Cells
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چکیده
منابع مشابه
Decreased Sp1 Expression Mediates Downregulation of SHIP2 in Gastric Cancer Cells
Past studies have shown that the Src homology 2-containing inositol 5-phosphatase 2 (SHIP2) is commonly downregulated in gastric cancer, which contributes to elevated activation of PI3K/Akt signaling, proliferation and tumorigenesis of gastric cancer cells. However, the mechanisms underlying the reduced expression of SHIP2 in gastric cancer remain unclear. While gene copy number variation analy...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2017
ISSN: 1422-0067
DOI: 10.3390/ijms18010220